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Carbonated soda treatment of phytobezoars

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– **Treatment**:
– Carbonated soda is used to dissolve phytobezoars.
– It can be administered by naso-gastric tube in children.
– Carbonated soda can be given orally and during endoscopy.
– In about 50% of cases, carbonated soda alone effectively dissolves gastric phytobezoars.
– Endoscopic techniques combined with carbonated soda lead to a success rate of up to 91.3%.

– **Other Medicinal Claims for Coca-Cola**:
Coca-Cola has been used as a treatment for phytobezoars.
– It can be given as a drinking beverage or as lavage.
– Different combinations of drink, injection, and irrigation have been used for treatment.
– Dosages of Coca-Cola in treatment can vary from 500mL to 3000mL.
– Alternative treatments include cellulase, acetylcysteine, and pancreatic enzymes.

– **Contraindications**:
– Trichobezoars do not respond to Coca-Cola treatment.
– Persimmon diospyrobezoars may require different treatments.
– Surgical approaches may be necessary in urgent cases with gastrointestinal bleeding.

– **Adverse Effects and Interactions**:
– Adverse effects like gastric ulcer and hyponatremia have been observed with papain.
– No adverse effects have been reported with Coca-Cola use.
– The impact of Coca-Cola on glucose levels during administration is unknown.

– **Pharmacology and Interactions**:
– Meat tenderizer has been used to dissolve stomach bezoars.
– Combining Coca-Cola with endoscopic methods leads to a 90% success rate.
– The dissolution mechanism involves low pH, CO2 bubbles, and sodium bicarbonate in Coca-Cola.
Coca-Cola’s acidity and CO2 release aid in bezoar disintegration.
Coca-Cola’s pH of 2.6, similar to gastric acid, softens and reduces bezoar size.

Carbonated soda treatment of phytobezoars is the use of carbonated soda to try to dissolve a phytobezoar. Bezoars consist of a solid and formed mass trapped in the gastrointestinal system, usually in the stomach. These can also form in other locations.


Carbonated soda has been proposed for the treatment of gastric phytobezoars. In about 50% of cases studied, carbonated soda alone was found to be effective in gastric phytobezoar dissolution. Unfortunately, this treatment can result in the potential of developing small bowel obstruction in a minority of cases, necessitating surgical intervention. It is one of many other stomach disorders that can have similar symptoms.[medical citation needed]

Gastric phytobezoars are a form of intestinal blockage and are seen in those with poor gastric motility. The preferred treatment of bezoars includes different therapies and/or fragmentation to avoid surgery. Phytobezoars are most common and consist of various undigested substances including lignin, cellulose, tannins, celery, pumpkin skin, grape skins, prunes, raisins, vegetables and fruits. Phytobezoars can form after eating persimmons and pineapples. These are more difficult to treat and are referred to as diospyrobezoars.

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